Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases.
Mosallanejad K, Kennedy SN, Bahleda KM, Slavik KM, Zhou W, Govande AA, Hancks DC, Kranzusch PJ, Kagan JC
Sci Immunol. 2023 Jan 20;8(79):eabp9765. doi: 10.1126/sciimmunol.abp9765. Epub 2023 Jan 20.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 186842 | pTRE3G-human cGAS-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186843 | pTRE3G-human cGASdeltaN-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186844 | pTRE3G-human cGAS-GFP | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186845 | pTRE3G-human cGASdeltaN-GFP | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186846 | pTRE3G-orangutan cGASdeltaN-GFP | Doxycycline-dependent expression of orangutan cGAS gene in mammalian cells by retroviral transduction |
| 186847 | pTRE3G-chimpanzee cGASdeltaN-GFP | Doxycycline-dependent expression of chimpanzee cGAS gene in mammalian cells by retroviral transduction |
| 186848 | pTRE3G-FLAG-human cGASdeltaN-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186849 | pTRE3G-FLAG-human cGAS-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186850 | pTRE3G-human cGASdeltaN C396/397A-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186851 | pTRE3G-HA-human cGAS | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186852 | pTRE3G-HA-human cGASdeltaN | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186853 | pTRE3G-human cGAS | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186854 | pTRE3G-human cGASdeltaN | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186855 | pTRE3G-human cGAS:154-522aa-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186856 | pTRE3G-human cGAS:156-522aa-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186857 | pTRE3G-human cGAS:158-522aa-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186858 | pTRE3G-human cGAS:162-522aa-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186859 | pTRE3G-human cGAS:164-522aa-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186860 | pTRE3G-human cGAS:166-522aa-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186861 | pTRE3G-gibbon cGASdeltaN-HA | Doxycycline-dependent expression of gibbon cGAS gene in mammalian cells by retroviral transduction |
| 186862 | pTRE3G-gibbon cGAS-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186863 | pTRE3G-marmoset cGASdeltaN-HA | Doxycycline-dependent expression of marmoset cGAS gene in mammalian cells by retroviral transduction |
| 186864 | pTRE3G-marmoset cGAS-HA | Doxycycline-dependent expression of marmoset cGAS gene in mammalian cells by retroviral transduction |
| 186865 | pTRE3G-rhesus macaque cGAS-HA | Doxycycline-dependent expression of rhesus macaque cGAS gene in mammalian cells by retroviral transduction |
| 186866 | pTRE3G-rhesus macaque cGASdeltaN-HA | Doxycycline-dependent expression of rhesus macaque cGAS gene in mammalian cells by retroviral transduction |
| 186867 | pTRE3G-WHG cGAS-HA | Doxycycline-dependent expression of white-handed gibbon cGAS gene in mammalian cells by retroviral transduction |
| 186868 | pTRE3G-WHG cGASdeltaN-HA | Doxycycline-dependent expression of white-handed gibbon cGAS gene in mammalian cells by retroviral transduction |
| 186869 | pTRE3G-crab-eating macaque cGAS-HA | Doxycycline-dependent expression of crab-eating macaque cGAS gene in mammalian cells by retroviral transduction |
| 186870 | pTRE3G-crab-eating macaque cGASdeltaN-HA | Doxycycline-dependent expression of crab-eating macaque cGAS gene in mammalian cells by retroviral transduction |
| 186871 | pTRE3G-orangutan cGAS-HA | Doxycycline-dependent expression of orangutan cGAS gene in mammalian cells by retroviral transduction |
| 186872 | pTRE3G-orangutan cGASdeltaN-HA | Doxycycline-dependent expression of orangutan cGAS gene in mammalian cells by retroviral transduction |
| 186873 | pTRE3G-chimpanzee cGAS-HA | Doxycycline-dependent expression of chimpanzee cGAS gene in mammalian cells by retroviral transduction |
| 186874 | pTRE3G-chimpanzee cGASdeltaN-HA | Doxycycline-dependent expression of chimpanzee cGAS gene in mammalian cells by retroviral transduction |
| 186875 | pTRE3G-mouse cGAS-HA | Doxycycline-dependent expression of mouse cGAS gene in mammalian cells by retroviral transduction |
| 186876 | pTRE3G-mouse cGASdeltaN-HA | Doxycycline-dependent expression of mouse cGAS gene in mammalian cells by retroviral transduction |
| 186877 | pTRE3G-mouse cGAS-GFP | Doxycycline-dependent expression of mouse cGAS gene in mammalian cells by retroviral transduction |
| 186878 | pTRE3G-mouse cGASdeltaN-GFP | Doxycycline-dependent expression of mouse cGAS gene in mammalian cells by retroviral transduction |
| 186879 | pTRE3G-FLAG-human cGASdeltaN-GFP | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186880 | pTRE3G-GFP-human cGASdeltaN | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186881 | pTRE3G-human cGASdeltaN-OMM | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186882 | pTRE3G-human cGASdeltaN-Pex | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186883 | pTRE3G-human cGASdeltaN-ER | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186884 | pTRE3G-NS3/4A | Doxycycline-dependent expression of NS3/4A protease gene in mammalian cells by retroviral transduction |
| 186885 | pTRE3G-NS3/4A S139A | Doxycycline-dependent expression of catalytically inactive NS3/4A protease gene (S140A) in mammalian cells by retroviral transduction |
| 186886 | pTRE3G-FLAG-human cGAS N-T2A-deltaN-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186887 | pLenti-CMV-human cGASdeltaN-OMM | Expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186888 | pLenti-CMV-orangutan cGASdeltaN-OMM | Expression of orangutan cGAS gene in mammalian cells by retroviral transduction |
| 186889 | pLenti-CMV-FLAG-orangutan cGASdeltaN-OMM | Expression of orangutan cGAS gene in mammalian cells by retroviral transduction |
| 186890 | pRRL-mouse cGAS #1-gRNA-Cas9-Puro | gRNA targeting mouse cGAS (with Cas9 insert) |
| 186891 | pRRL-mouse cGAS #2-gRNA-Cas9-Puro | gRNA targeting mouse cGAS (with Cas9 insert) |
| 186892 | pRRL-mouse STING #1-gRNA-Cas9-Puro | gRNA targeting mouse STING (with Cas9 insert) |
| 186893 | pRRL-mouse STING #2-gRNA-Cas9-Puro | gRNA targeting mouse STING (with Cas9 insert) |
| 186894 | pTRE3G-human cGASdeltaN R255E-HA | Doxycycline-dependent expression of human cGAS gene (with R255E mutation) in mammalian cells by retroviral transduction |
| 186895 | pTRE3G-mouse cGAS:145-508aa-HA | Doxycycline-dependent expression of mouse cGAS gene in mammalian cells by retroviral transduction |
| 186896 | pTetOne-human cGAS-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186897 | pTetOne-human cGASdeltaN-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186898 | pTetOne-orangutan cGASdeltaN-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |
| 186899 | pTetOne-FLAG-human cGASdeltaN-HA | Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction |