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ISX-9 potentiates CaMKIIdelta-mediated BMAL1 activation to enhance circadian amplitude.

Li H, Ou J, Li Y, Xu N, Li Q, Wu P, Peng C, Tang YC, Chang HC
Commun Biol. 2022 Jul 28;5(1):750. doi: 10.1038/s42003-022-03725-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
186818pGL3-Camk2aFluorescent reporter for Camk2a expression
186819pGL3-Camk2bFluorescent reporter for Camk2b expression
186820pGL3-Camk2dFluorescent reporter for Camk2d expression
186821pGl3-Camk2gFluorescent reporter for Camk2g expression
186822pGL3-DbpFluorescent reporter for Dbp expression
186823pGL3-rev-erbαFluorescent reporter for rev-erbα expression
186824pCAGGS-BMAL1Expresses BMAL1 in mammalian cells
186825pCAGGS-FLAG-CaMKIIAExpresses FLAG-CaMKIIA in mammalian cells
186826pCAGGS-FLAG-CaMKIIBExpresses FLAG-CaMKIIB in mammalian cells
186827pCAGGS-FLAG-CaMKIIDExpresses FLAG-CaMKIID in mammalian cells
186828pCAGGS-FLAG-CaMKIIGExpresses FLAG-CaMKIIG in mammalian cells
186829pCAGGS-FLAG-BMAL1Expresses FLAG-BMAL1 in mammalian cells
186830pCAGGS-FLAG-CaMKIID-K43MExpresses FLAG-CaMKIID-K43M in mammalian cells
186831pCAGGS-FLAG-BMAL1-S513AExpresses FLAG-BMAL1-S513A in mammalian cells
186832pCAGGS-FLAG-BMAL1-S515AExpresses FLAG-BMAL1-S515A in mammalian cells
186833pCAGGS-FLAG-BMAL1-S516AExpresses FLAG-BMAL1-S516A in mammalian cells
186834pCAGGS-FLAG-BMAL1-S519AExpresses FLAG-BMAL1-S519A in mammalian cells
186835pCAGGS-FLAG-BMAL1-S513A/S515A/S516AExpresses FLAG-BMAL1-S513A/S515A/S516A in mammalian cells

Antibodies from Article