MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis.
Zouiouich M, Di Mattia T, Martinet A, Eichler J, Wendling C, Tomishige N, Grandgirard E, Fuggetta N, Fromental-Ramain C, Mizzon G, Dumesnil C, Carpentier M, Reina-San-Martin B, Mathelin C, Schwab Y, Thiam AR, Kobayashi T, Drin G, Tomasetto C, Alpy F
J Cell Biol. 2022 Jun 6;221(6). pii: 213116. doi: 10.1083/jcb.202110044. Epub 2022 Apr 7.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 186471 | pQCXIP GFP-MOSPD2 W201E | Expression of human MOSPD2 (mutant W201E, unable to bind lipid droplets) fused to EGFP in mammalian cells |
| 186472 | pQCXIP mScarlet-MOSPD2 WT | Expression of human MOSPD2 fused to mScarlet in mammalian cells |
| 186476 | pQCXIP mScarlet-MOSPD2 RD/LD | Expression of human MOSPD2 (mutant R404D/L406D, unable to bind FFAT motifs) fused to mScarlet in mammalian cells |
| 186477 | pQCXIP mScarlet-MOSPD2 W201E | Expression of human MOSPD2 (mutant W201E, unable to bind lipid droplets) fused to mScarlet in mammalian cells |
| 186572 | pQCXIP mScarlet-ER [TM(SAC1)] | Expression of the Endoplasmic Reticulum marker mScarlet-ER [TM(SAC1)] in mammalian cells |