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Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.

Danis C, Dupre E, Zejneli O, Caillierez R, Arrial A, Begard S, Mortelecque J, Eddarkaoui S, Loyens A, Cantrelle FX, Hanoulle X, Rain JC, Colin M, Buee L, Landrieu I
Mol Ther. 2022 Apr 6;30(4):1484-1499. doi: 10.1016/j.ymthe.2022.01.009. Epub 2022 Jan 7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
186033pHEN2 F8-2Express VHH F8-2 with 3 c-myc tag in E. coli periplasm
186034pMCherry F8-2Express VHH F8-2 as a mCherry fusion in mammalian cells

Antibodies from Article