The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo.
Sabharwal A, Kar B, Restrepo-Castillo S, Holmberg SR, Mathew ND, Kendall BL, Cotter RP, WareJoncas Z, Seiler C, Nakamaru-Ogiso E, Clark KJ, Ekker SC
CRISPR J. 2021 Dec;4(6):799-821. doi: 10.1089/crispr.2021.0061. Epub 2021 Nov 30.
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PubMed
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 196496 | ND4-FusXTBE-Left TALE | Expresses left-side TALE-DddAtox Cterm half ND4-FusXTBE in mammalian cells |
| 196497 | ND4-FusXTBE-Right TALE | Expresses Right-side TALE-DddAtox Nterm half ND4-FusXTBE in mammalian cells |
| 196498 | ND2-FusXTBE-Left TALE | Expresses left-side TALE-DddAtox Cterm half ND2-FusXTBE in mammalian cells |
| 196499 | ND2-FusXTBE-Right TALE | Expresses Right-side TALE-DddAtox Nterm half ND2-FusXTBE in mammalian cells |
| 196500 | Cox1-FusXTBE-Left TALE | Expresses left-side TALE-DddAtox Cterm half Cox1-FusXTBE in mammalian cells |
| 196501 | Cox1-FusXTBE-Right TALE | Expresses Right-side TALE-DddAtox Nterm half Cox1-FusXTBE in mammalian cells |
| 196502 | Cox1-FusXTBE-Left TALE | Expresses left-side TALE–DddAtox N term half cox1-FusXTBE in zebrafish |
| 196503 | Cox1-FusXTBE-RightTALE | Expresses right-side TALE–DddAtox C term half cox1-FusXTBE in zebrafish |
| 196504 | Cox3-FusXTBE-Left TALE | Expresses left-side TALE–DddAtox N term half cox3-FusXTBE in zebrafish |
| 196505 | Cox3-FusXTBE-RightTALE | Expresses right-side TALE–DddAtox C term half cox3-FusXTBE in zebrafish |
| 196506 | tl1-FusXTBE-Left TALE | Expresses left-side TALE–DddAtox N term half tl1-FusXTBE in zebrafish |
| 196507 | tl1-FusXTBE-RightTALE | Expresses left-side TALE–DddAtox N term half tl1-FusXTBE in zebrafish |
| 201397 | FusXTBE-1397-N | Expresses N terminus half of DddAtox in mammalian cells |
| 201398 | FusXTBE-1397-C | Expresses C terminus half of DddAtox in mammalian cells |