Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex.
Mich JK, Graybuck LT, Hess EE, Mahoney JT, Kojima Y, Ding Y, Somasundaram S, Miller JA, Kalmbach BE, Radaelli C, Gore BB, Weed N, Omstead V, Bishaw Y, Shapovalova NV, Martinez RA, Fong O, Yao S, Mortrud M, Chong P, Loftus L, Bertagnolli D, Goldy J, Casper T, Dee N, Opitz-Araya X, Cetin A, Smith KA, Gwinn RP, Cobbs C, Ko AL, Ojemann JG, Keene CD, Silbergeld DL, Sunkin SM, Gradinaru V, Horwitz GD, Zeng H, Tasic B, Lein ES, Ting JT, Levi BP
Cell Rep. 2021 Mar 30;34(13):108754. doi: 10.1016/j.celrep.2021.108754.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 163494 | AiP11402-pAAV-AiE0058h-minBG-SYFP2-WPRE3-BGHpA (Alias: CN1402) | AiE0058h is an enhancer sequence designed to drive AAV-mediated transgene expression in L4/5_IT cortical neurons |
| 163495 | CN1457-rAAV-eHGT_078h-minBG-SYFP2-WPRE3-BGHpA | Direct-expressing SYFP2 AAV Virus |
| 163497 | CN1253-scAAV-eHGT_017h-minBG-SYFP2-WPRE3-BGHpA | Direct-expressing SYFP2 AAV Virus |
| 163498 | CN1621-rAAV-hsA2-eHGT_128h-minRho-SYFP2-WPRE3-BGHpA | Direct-expressing SYFP2 AAV Virus |
| 163500 | AiP11408-pAAV-AiE0064h-minBG-SYFP2-WPRE3-BGHpA (Alias: CN1408) | AiE0064h is an enhancer sequence designed to drive AAV-mediated transgene expression in Pvalb+ and Sst+ cortical interneurons |
| 163501 | CN1525-rAAV-hsA2-eHGT_079h-minRho-SYFP2-WPRE3-BGHpA | Direct-expressing SYFP2 AAV Virus |
| 163502 | CN1528-rAAV-hsA2-eHGT_082h-minRho-SYFP2-WPRE3-BGHpA | Direct-expressing SYFP2 AAV Virus |
| 163503 | AiP11633 - pAAV-hsA2-AiE0140h-minRho-SYFP2-WPRE3-BGHpA (Alias: CN1633) | Direct-expressing SYFP2 AAV Virus |
| 163504 | AiP12045-pAAV-3xSP10ins-AiE0359h-minRho-SYFP2-WPRE3-BGHpA (Alias: CN2045) | AiE0359h is an enhancer sequence designed to drive AAV-mediated transgene expression in Pvalb+ cortical interneurons and cerebellar Purkinje cells |