DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.
Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee H, Koppula P, Wu S, Zhuang L, Fang B, Poyurovsky MV, Olszewski K, Gan B
Nature. 2021 May;593(7860):586-590. doi: 10.1038/s41586-021-03539-7. Epub 2021 May 12.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 186022 | lentiCRISPR v2-sgDHODH-4 | knock out DHODH in mammalian cells |
| 186023 | lentiCRISPR v2-sgDHODH-2 | knock out DHODH in mammalian cells |
| 186024 | lentiCRISPR v2-sgACSL4 | knock out ACSL4 in mammalian cells |
| 186025 | lentiCRISPR v2-sgCOQ2 | knock out COQ2 in mammalian cells |
| 186026 | lentiCRISPR v2-sgFSP1 | knock out FSP1 in mammalian cells |