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Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer.

Westcott PMK, Sacks NJ, Schenkel JM, Ely ZA, Smith O, Hauck H, Jaeger AM, Zhang D, Backlund CM, Beytagh MC, Patten JJ, Elbashir R, Eng G, Irvine DJ, Yilmaz OH, Jacks T
Nat Cancer. 2021 Oct;2(10):1071-1085. doi: 10.1038/s43018-021-00247-z. Epub 2021 Sep 30. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
185661dimSIINshApc-expressing lentiviruses with varius levels of expression of SIINFEKL
185662hiSIINshApc-expressing lentiviruses with varius levels of expression of SIINFEKL
185663loSIINshApc-expressing lentiviruses with varius levels of expression of SIINFEKL
185664medSIINshApc-expressing lentiviruses with varius levels of expression of SIINFEKL
185665midSIINshApc-expressing lentiviruses with varius levels of expression of SIINFEKL
185666noSIINshApc-expressing lentiviruses with no expression of SIINFEKL

Antibodies from Article