Conformational exchange at a C(2)H(2) zinc-binding site facilitates redox sensing by the PML protein.
Bregnard TA, Fairchild D, Erlandsen H, Semenova IV, Szczepaniak R, Ahmed A, Weller SK, Korzhnev DM, Bezsonova I
Structure. 2023 Sep 7;31(9):1086-1099.e6. doi: 10.1016/j.str.2023.06.014. Epub 2023 Jul 19.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 185631 | pGEX-PML RING | expression of GST-tagged PML RING domain in bacterial cells |
| 185632 | pGEX-PML B-box1 WT | expression of GST-tagged wild-type PML B-box1 domain in bacterial cells |
| 185640 | pGEX-PML B-box1 C4C4 | expression of GST-tagged mutant PML B-box1 H155C/H161C domain in bacterial cells |
| 185641 | pGEX-PML B-box1 W157E | expression of GST-tagged mutant PML B-box1 W157E domain in bacterial cells |
| 185642 | pGEX-PML B-box1 F158E | expression of GST-tagged mutant PML B-box1 F158E domain in bacterial cells |