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CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells.

Werder RB, Liu T, Abo KM, Lindstrom-Vautrin J, Villacorta-Martin C, Huang J, Hinds A, Boyer N, Bullitt E, Liesa M, Silverman EK, Kotton DN, Cho MH, Zhou X, Wilson AA
Sci Adv. 2022 Jul 15;8(28):eabo6566. doi: 10.1126/sciadv.abo6566. Epub 2022 Jul 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
185549pLV-GG-hUbC-EBPF2-gRNA-DSPLentiviral backbone with EBFP2 reporter and gRNA targeting DSP
185550pLV-GG-hUbC-EBPF2-gRNA-FAM13ALentiviral backbone with EBFP2 reporter and gRNA targeting FAM13A
185551pLV-GG-hUbC-EBPF2-gRNA-HHIPLentiviral backbone with EBFP2 reporter and gRNA targeting HHIP
185552pLV-GG-hUbC-EBPF2-gRNA-SOX4Lentiviral backbone with EBFP2 reporter and gRNA targeting SOX4
185554pLV-GG-hUbC-EBPF2-gRNA-ADGRG6Lentiviral backbone with EBFP2 reporter and gRNA targeting ADGRG6
185555pLV-GG-hUbC-EBPF2-gRNA-MFAP2Lentiviral backbone with EBFP2 reporter and gRNA targeting MFAP2
185556pLV-GG-hUbC-EBPF2-gRNA-TGFB2Lentiviral backbone with EBFP2 reporter and gRNA targeting TGFB2
185557pLV-GG-hUbC-EBPF2-gRNA-RBMS3Lentiviral backbone with EBFP2 reporter and gRNA targeting RBMS3
212314pLV-GG-hUBC-EBFP2Lentiviral backbone with EBFP2 reporter

Antibodies from Article