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Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission.

Cuhadar U, Calzado-Reyes L, Pascual-Caro C, Aberra AS, Ritzau-Jost A, Aggarwal A, Ibata K, Podgorski K, Yuzaki M, Geis C, Hallerman S, Hoppa MB, de Juan-Sanz J
Cell Rep. 2024 May 28;43(5):114186. doi: 10.1016/j.celrep.2024.114186. Epub 2024 May 2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
185537CamKII-LGI1-pHluorinExpresses LGI1-pHluorin under the CamKII promoter
185538CamKII-LGI1-pHmScarletExpresses LGI1-pHmScarlet under the CamKII promoter
185539CamKII-ADAM23-pHluorinExpresses ADAM23-pHluorin under the CamKII promoter
185540CamKII-LGI1-S473L-pHluorinExpresses mutant S473L LGI1-pHluorin under the CamKII promoter
185541CamKII-LGI1-Y433A-pHluorinExpresses mutant Y433A LGI1-pHluorin under the CamKII promoter
185542CamKII-LGI1-R474Q-pHluorinExpresses mutant R474Q LGI1-pHluorin under the CamKII promoter
185543CamKII-LGI1-T380A-pHluorinExpresses mutant T380A LGI1-pHluorin under the CamKII promoter
185544CamKII-LGI1-E383A-pHluorinExpresses mutant E383A LGI1-pHluorin under the CamKII promoter
185545CamKII-LGI1-C200R-pHluorinExpresses mutant C200R LGI1-pHluorin under the CamKII promoter
185546CMV-IgK-pHluorin-TM-mRubyExpresses surface-localized pHluorin fused to intracellular expression of mRuby under CMV promoter

Antibodies from Article