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Timothy Ley Lab: Mammalian expression plasmids for FLT3 wildtype and common AML mutant FLT3 proteins

Unpublished

Plasmids from Article

ID Plasmid Purpose
184778FLT3-MSCV-IRES-GFPExpresses wildtype FLT3 in mammalian cells
184779FLT3-ITD-MSCV-IRES-GFPExpresses FLT3-ITD (internal tandem duplication) constitutively active mutant in mammalian cells
184780FLT3-D835Y-MSCV-IRES-GFPExpresses FLT3 D835Y activating tyrosine kinase domain mutant in mammalian cells

Antibodies from Article