Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells.
Qian F, Nettleford SK, Zhou J, Arner BE, Hall MA, Sharma A, Annageldiyev C, Rossi RM, Tukaramrao DB, Sarkar D, Hegde S, Gandhi UH, Finch ER, Goodfield L, Quickel MD, Claxton DF, Paulson RF, Prabhu KS
Cell Rep. 2023 Jul 25;42(7):112794. doi: 10.1016/j.celrep.2023.112794. Epub 2023 Jul 18.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 184556 | pLV hU6-sgKRAS hUbC-dCas9-KRAB-T2a-GFP1 | Knockdown of murine KRAS gene by targeting the promoter region via CRISPRi system |
| 184557 | pLV hU6-sgKRAS hUbC-dCas9-KRAB-T2a-GFP2 | Knockdown of murine KRAS gene by targeting the promoter region via CRISPRi system |