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Directed evolution of adeno-associated virus for efficient gene delivery to microglia.

Lin R, Zhou Y, Yan T, Wang R, Li H, Wu Z, Zhang X, Zhou X, Zhao F, Zhang L, Li Y, Luo M
Nat Methods. 2022 Jul 25. pii: 10.1038/s41592-022-01547-7. doi: 10.1038/s41592-022-01547-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
184539rAAV2/cMGAAV packaging plasmid, expressing Rep2 and AAV-cMG capsid
184540rAAV2/MG1.1AAV packaging plasmid, expressing Rep2 and AAV-MG1.1 capsid
184541rAAV2/MG1.2AAV packaging plasmid, expressing Rep2 and AAV-MG1.2 capsid
184542rAAV2/cMG.WPPAAV packaging plasmid, expressing Rep2 and AAV-cMG.WPP capsid
184543rAAV2/cMG.QRPAAV packaging plasmid, expressing Rep2 and AAV-cMG.QRP capsid

Antibodies from Article