Targeting the lung epithelium after intravenous delivery by directed evolution of underexplored sites on the AAV capsid.
Goertsen D, Goeden N, Flytzanis NC, Gradinaru V
Mol Ther Methods Clin Dev. 2022 Aug 1;26:331-342. doi: 10.1016/j.omtm.2022.07.010. eCollection 2022 Sep 8.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 184592 | pUCmini-iCAP-AAV9.452sub.LUNG1 | non-standard AAV2 rep-AAV9.452sub.LUNG1 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system for mouse lung transduction after intravenous injection |