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Decorating chromatin for enhanced genome editing using CRISPR-Cas9.

Chen E, Lin-Shiao E, Trinidad M, Saffari Doost M, Colognori D, Doudna JA
Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2204259119. doi: 10.1073/pnas.2204259119. Epub 2022 Dec 2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
184464PRDM9(KRAB-SSXRD-PR/SET-ZF1-dC)-Cas9Plasmid encoding PRDM9-Cas9 fusion under CMV promoter
186699PRDM9dC(KRAB-SSXRD-PR/SET-dC)-Cas9Plasmid encoding PRDM9dC-Cas9 fusion under CMV promoter
186700SETD2(SET)-Cas9Plasmid encoding SETD2-Cas9 fusion under CMV promoter
186701SETMAR-Cas9Plasmid encoding SETMAR-Cas9 fusion under CMV promoter

Antibodies from Article