A general approach for engineering RTKs optically controlled with far-red light.
Leopold AV, Thankachan S, Yang C, Gerashchenko D, Verkhusha VV
Nat Methods. 2022 Jul;19(7):871-880. doi: 10.1038/s41592-022-01517-z. Epub 2022 Jun 9.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 183994 | eDrFGFR1 | Optically controlled eDrFGFR1 expression in mammalian cells |
| 183995 | eDrHER2 | Optically controlled eDrHER2 expression in mammalian cells |
| 183996 | eDrTrkA | Optically controlled eDrTrkA expression in mammalian cells |
| 183997 | eDrTrkB | Optically controlled eDrTrkB expression in mammalian cells |
| 183998 | eDrIR1 | Optically controlled eDrIR1 expression in mammalian cells |
| 183999 | eDrMet | Optically controlled eDrcMet expression in mammalian cells |
| 184000 | eDrEGFR | Optically controlled eDrEGFR expression in mammalian cells |
| 184001 | eDrcKIT | Optically controlled eDrcKIT expression in mammalian cells |
| 184002 | AAV2/9-CW3SL-mCherry-DrTrkB | AAV production for expression of optically controlled eDrTrkB with N-terminal fusion of mCherry |
| 184003 | AAV2/9-shMBVR-HO1-Fd-Fnr-CW3SL | AAV production |