A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver.
Zheng C, Liang SQ, Liu B, Liu P, Kwan SY, Wolfe SA, Xue W
Mol Ther. 2022 Mar 2;30(3):1343-1351. doi: 10.1016/j.ymthe.2022.01.005. Epub 2022 Jan 5.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 183538 | AAV8-cPE-N | Deliver a split compact Prime Editor in vivo |
| 183539 | AAV8-cPE-C | Deliver a split compact Prime Editor in vivo |
| 183549 | cPE | Expresses compact Prime Editor in mammalian cells |