Structural diversity of the SARS-CoV-2 Omicron spike.
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell. 2022 Jun 2;82(11):2050-2068.e6. doi: 10.1016/j.molcel.2022.03.028. Epub 2022 Mar 25.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 180423 | pαH-S-GSAS-OMICRON | Mammalian cell expression of SARS-CoV-2 Spike protein variant OMICRON with furin side replaced by GSAS |
| 180424 | pαH-S-RRAR-OMICRON | Mammalian cell expression of SARS-CoV-2 Spike protein variant OMICRON with furin side intact |
| 180593 | pαH-S-GSAS-2P-OMICRON | Mammalian cell expression of SARS-CoV-2 Spike protein variant OMICRON with furin side replaced by GSAS and with 2 Proline substitution at 986 and 987 |
| 182575 | pαH-S-GSAS-B.1.617.2.v1 | Mammalian cell expression of SARS-CoV-2 Spike protein Delta variant, furin side replaced by GSAS, 2 Proline at 986 and 987 plus T19R-G142D-del156/157-R158G-L452R-T478K-D614G-P681R-D950N |
| 183515 | pαH-rS2d-HexaPro | Mammalian cell expression of SARS-CoV-2 Spike protein rS2d-HexaPro with (682-685) furin side replaced with GSAS and mutation S383C, D985C, F817P, A892P, A899P, A942P, K986P,V987P |
| 183516 | pαH-rS2d | Mammalian cell expression of SARS-CoV-2 Spike protein S-GSAS-rS2d with (682-685) furin side replaced with GSAS and mutation S383C, D985C |