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HLA-G gene editing in tumor cell lines as a novel alternative in cancer immunotherapy.

Palma MB, Tronik-Le Roux D, Amin G, Castaneda S, Mobbs AM, Scarafia MA, La Greca A, Daouya M, Poras I, Inda AM, Moro LN, Carosella ED, Garcia MN, Miriuka SG
Sci Rep. 2021 Nov 12;11(1):22158. doi: 10.1038/s41598-021-01572-0. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
182551pSpCas9-Puro HLAG-2A-sgRNACas9 from S.pyogenes with 2A-Puro, and the 2A-sgRNA to targeting exon 2 of human HLA-G gene
182552pSpCas9-Puro HLAG-2B-sgRNACas9 from S.pyogenes with 2A-Puro, and the 2B-sgRNA to targeting exon 2 of human HLA-G gene

Antibodies from Article