Skip to main content
Addgene

Aging-relevant human basal forebrain cholinergic neurons as a cell model for Alzheimer's disease.

Ma S, Zang T, Liu ML, Zhang CL
Mol Neurodegener. 2020 Oct 21;15(1):61. doi: 10.1186/s13024-020-00411-6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
182233pCSC-ASCL1-IRES-GFP-T2A-Sox11To convert human skin fibroblasts into induced basal forebrain cholinergic neurons (hiBFCNs) in combination with LHX8, GBX1, FGF2 and two small molecules, forskolin and LDN-193189
182234pCSC-ASCL1-IRES-Sox11To convert human skin fibroblasts into induced basal forebrain cholinergic neurons (hiBFCNs) in combination with LHX8, GBX1, FGF2 and two small molecules, forskolin and LDN-193189
182235pCSC-LHX8-IRES-GBX1To convert human skin fibroblasts into induced basal forebrain cholinergic neurons (hiBFCNs) in combination with ASCL1, Sox11, FGF2 and two small molecules, forskolin and LDN-193189

Antibodies from Article