Aging-relevant human basal forebrain cholinergic neurons as a cell model for Alzheimer's disease.
Ma S, Zang T, Liu ML, Zhang CL
Mol Neurodegener. 2020 Oct 21;15(1):61. doi: 10.1186/s13024-020-00411-6.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
182233 | pCSC-ASCL1-IRES-GFP-T2A-Sox11 | To convert human skin fibroblasts into induced basal forebrain cholinergic neurons (hiBFCNs) in combination with LHX8, GBX1, FGF2 and two small molecules, forskolin and LDN-193189 |
182234 | pCSC-ASCL1-IRES-Sox11 | To convert human skin fibroblasts into induced basal forebrain cholinergic neurons (hiBFCNs) in combination with LHX8, GBX1, FGF2 and two small molecules, forskolin and LDN-193189 |
182235 | pCSC-LHX8-IRES-GBX1 | To convert human skin fibroblasts into induced basal forebrain cholinergic neurons (hiBFCNs) in combination with ASCL1, Sox11, FGF2 and two small molecules, forskolin and LDN-193189 |