Quantitative Measurement of Cytosolic and Nuclear Penetration of Oligonucleotide Therapeutics.
Deprey K, Batistatou N, Debets MF, Godfrey J, VanderWall KB, Miles RR, Shehaj L, Guo J, Andreucci A, Kandasamy P, Lu G, Shimizu M, Vargeese C, Kritzer JA
ACS Chem Biol. 2022 Jan 15. doi: 10.1021/acschembio.1c00830.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 182202 | AAV-H2GH | Adeno-associated viral vector to express histone2B-HaloTag-GFP fusion, a nuclear-localized Halotag-GFP fusion construct |
| 220988 | AAV-HGM (optimized) | Adeno-associated viral vector to express HaloTag-GFP-mito fusion, a cytosolic-localized Halotag-GFP fusion construct |