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Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition.

Govorunova EG, Gou Y, Sineshchekov OA, Li H, Lu X, Wang Y, Brown LS, St-Pierre F, Xue M, Spudich JL
Nat Neurosci. 2022 Jun 20. pii: 10.1038/s41593-022-01094-6. doi: 10.1038/s41593-022-01094-6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
177336HcKCR1_mCherry_pcDNA3.1Expresses KCR1 in mammalian cells
177337HcKCR2_mCherry_pcDNA3.1Expresses KCR2 in mammalian cells
182021pAAV-CAG-HcKCR1-EYFPExpress light-gated potassium channel HcKCR1-EYFP in mammalian cells
182022pAAV-CAG-HcKCR2-EYFPExpress light-gated potassium channel HcKCR2-EYFP in mammalian cells

Antibodies from Article