Addgene: A genome-scale screen for synthetic drivers of T cell proliferation.

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Neville Sanjana
Legut et al

A genome-scale screen for synthetic drivers of T cell proliferation.

Legut M, Gajic Z, Guarino M, Daniloski Z, Rahman JA, Xue X, Lu C, Lu L, Mimitou EP, Hao S, Davoli T, Diefenbach C, Smibert P, Sanjana NE
Nature. 2022 Mar;603(7902):728-735. doi: 10.1038/s41586-022-04494-7. Epub 2022 Mar 16. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

Showing 1 to 6 of 6 entries

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Search table:

ID	Plasmid	Purpose
181975	pOT_6 - lenti-EFS-FMC6.3-BBz-2A-puro-2A-tNGFR	Expresses anti-CD19 CAR (with 4-1BB signaling domain) linked to puromycin resistance via P2A and to human truncated NGFR via T2A for lentiviral delivery.
181974	pOT_5 - lenti-EFS-FMC6.3-28z-2A-puro-2A-tNGFR	Expresses anti-CD19 CAR (with CD28 signaling domain) linked to puromycin resistance via P2A and to human truncated NGFR via T2A for lentiviral delivery.
181973	pOT_4 - lenti-EFS-FMC6.3-BBz-2A-puro-2A-LTBR	Expresses anti-CD19 CAR (with 4-1BB signaling domain) linked to puromycin resistance via P2A and to human LTBR via T2A for lentiviral delivery.
181972	pOT_3 - lenti-EFS-FMC6.3-28z-2A-puro-2A-LTBR	Expresses anti-CD19 CAR (with CD28 signaling domain) linked to puromycin resistance via P2A and to human LTBR via T2A for lentiviral delivery.
181971	pOT_2 - lenti-EFS-tNGFR-2A-puro	Expresses human truncated NGFR linked to puromycin resistance via P2A for lentiviral delivery.
181970	pOT_1 - lenti-EFS-LTBR-2A-puro	Expresses human LTBR linked to puromycin resistance via P2A for lentiviral delivery.

Antibodies from Article