Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals.
Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE
Nat Commun. 2013;4:2034. doi: 10.1038/ncomms3034.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 181865 | pAAV-MCU-tDimer | Expresses tDimer-tagged mitochondrial calcium uniporter (MCU) under control of the CaMKIIa promoter |
| 181866 | pAAV-MCU-EGFP | Expresses GFP-tagged mitochondrial calcium uniporter (MCU) under control of the CaMKIIa promoter |
| 181867 | pAAV-shMcu-2 | Expresses Mcu-targeted shRNA under control of the U6 promoter and hrGFP under control of the synthetic CAG promoter |
| 181868 | pAAV-shMcu-1 | Expresses Mcu-targeted shRNA under control of the U6 promoter and hrGFP under control of the synthetic CAG promoter |