Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo.
Devireddy S, Ferguson SM
J Cell Biol. 2022 Feb 7;221(2):e202104044. doi: 10.1083/jcb.202104044. Epub 2021 Dec 17.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 180439 | STR-KDEL_PGRN-SBP-mCherry | Co-expresses (via IRES) streptavidin-KDEL and Progranulin-SBP-mCherry |
| 180440 | STR-KDEL_PSAP-SBP-mCherry | Co-expresses (via IRES) streptavidin-KDEL and Prosaposin-SBP-mCherry |