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A Two-tiered functional screen identifies herpesviral transcriptional modifiers and their essential domains.

Morgens DW, Nandakumar D, Didychuk AL, Yang KJ, Glaunsinger BA
PLoS Pathog. 2022 Jan 18;18(1):e1010236. doi: 10.1371/journal.ppat.1010236. eCollection 2022 Jan. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
180272KSHV Tiling LibrarysgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.

Antibodies from Article