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Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2.

Sangree AK, Griffith AL, Szegletes ZM, Roy P, DeWeirdt PC, Hegde M, McGee AV, Hanna RE, Doench JG
Nat Commun. 2022 Mar 14;13(1):1318. doi: 10.1038/s41467-022-28884-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
179084pRDA_151nuclease Cas expression
179085pRDA_152nuclease Cas expression
179086pRDA_153nuclease Cas expression
179087pRDA_154nuclease Cas expression
179088pRDA_155nuclease Cas expression
179089pRDA_156nuclease Cas expression
179090pRDA_157nuclease Cas expression
179091pRDA_275nuclease Cas expression
179092pRDA_381nuclease Cas expression
179093pRDA_449nuclease Cas expression
179094pRDA_450nuclease Cas expression
179095pRDA_336BE Cas expression
179096pRDA_478BE Cas expression
179097pRDA_426BE Cas expression
179098pRDA_429BE Cas expression
179099pRDA_479BE Cas expression

Antibodies from Article