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Aggregation-prone GFAP mutation in Alexander disease validated using a zebrafish model.

Lee SH, Nam TS, Kim KH, Kim JH, Yoon W, Heo SH, Kim MJ, Shin BA, Perng MD, Choy HE, Jo J, Kim MK, Choi SY
BMC Neurol. 2017 Sep 7;17(1):175. doi: 10.1186/s12883-017-0938-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
178961pSYC-176Expresses human GFAP fused to 3xFLAG tag in mammalian cells
178962pSYC-190Expresses human GFAP (R79C) mutant fused to 3xFLAG tag in mammalian cells
178963pSYC-201Human GFAP fused to 3xFLAG tag and EGFP driven by zebrafish gfap promoter for Tol2 mediated recombination
178964pSYC-204Human GFAP (R79C) mutant fused to 3xFLAG tag and EGFP driven by zebrafish gfap promoter for Tol2 mediated recombination

Antibodies from Article