Molecular basis of astrocyte diversity and morphology across the CNS in health and disease.
Endo F, Kasai A, Soto JS, Yu X, Qu Z, Hashimoto H, Gradinaru V, Kawaguchi R, Khakh BS
Science. 2022 Nov 4;378(6619):eadc9020. doi: 10.1126/science.adc9020. Epub 2022 Nov 4.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 178960 | PZac2.1 gfaABC1D-NLS-SaCas9-3xHA-NLS bGH | Expresses saCas9 protein specifically in astrocytes |
| 179117 | Pzac2.1 U6-Fermt2 sgRNA1, 2, 3_gfaABC1D mcherry SV40 | Expresses Fermt2 sgRNAs under the U6 promoter and mcherry protein specifically in astrocytes |
| 179119 | Pzac2.1 U6-Ezr sgRNA1, 2, 3_gfaABC1D mcherry SV40 | Expresses Ezr sgRNAs under the U6 promoter and mcherry protein specifically in astrocytes |
| 179120 | Pzac2.1 U6-control sgRNA1, 2, 3_gfaABC1D mcherry SV40 | Expresses control sgRNAs under the U6 promoter and mcherry protein specifically in astrocytes |