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Talin variant P229S compromises integrin activation and associates with multifaceted clinical symptoms.

Azizi L, Varela L, Turkki P, Mykuliak VV, Korpela S, Ihalainen TO, Church J, Hytonen VP, Goult BT
Hum Mol Genet. 2022 Jul 21. pii: 6647920. doi: 10.1093/hmg/ddac163. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
177870mTln1-F2-pET151Expresses mouse Talin 1 F2 domain in bacterial cells
177871mTln1-F2-P229S-pET151Expresses mouse Talin 1 F2-P229S domain in bacterial cells
177876mTln1-F2-P229L-pET151Expresses mouse Talin 1 F2-P229L domain in bacterial cells
177877mTln1-F2F3-pET151Expresses mouse Talin 1 F2F3 domains in bacterial cells
177878mTln1-F2F3-P229S-pET151Expresses mouse Talin 1 F2F3-P229S domains in bacterial cells
177879mTln1-F2F3-P229L-pET151Expresses mouse Talin 1 F2F3-P229L domains in bacterial cells

Antibodies from Article