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GABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoter.

Hoshino C, Konno A, Hosoi N, Kaneko R, Mukai R, Nakai J, Hirai H
Mol Brain. 2021 Feb 15;14(1):33. doi: 10.1186/s13041-021-00746-1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
177316pAAV mGAD65(delE1) GFP WPRE SV40pATo produce the AAV vector that expresses GFP under the control of the mGAD65 promoter. The mGAD65 promoter has highly specificity to GABAergic interneurons.

Antibodies from Article