LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer.
Murray CW, Brady JJ, Han M, Cai H, Tsai MK, Pierce SE, Cheng R, Demeter J, Feldser DM, Jackson PK, Shackelford DB, Winslow MM
Nat Commun. 2022 Feb 28;13(1):1090. doi: 10.1038/s41467-022-28619-8.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 177237 | hU6-sgNT1 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses non-targeting gRNA |
| 177238 | hU6-sgNT2 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses non-targeting gRNA |
| 177239 | hU6-sgNT3 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses non-targeting gRNA |
| 177240 | hU6-sgNeo1 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses neomycin gRNA |
| 177241 | hU6-sgNeo2 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses neomycin gRNA |
| 177242 | hU6-sgNeo3 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses neomycin gRNA |
| 177243 | hU6-sgLkb1_IW (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Lkb1 gRNA |
| 177244 | hU6-sgLkb1_v2 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Lkb1 gRNA |
| 177245 | hu6-sgCebpa_v1 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Cebpa gRNA |
| 177246 | hu6-sgCebpa_v2 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Cebpa gRNA |
| 177247 | hu6-sgCebpb_v1 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Cebpb gRNA |
| 177248 | hu6-sgCebpb_v2 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Cebpb gRNA |
| 177249 | hu6-sgCebpd_v1 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Cebpd gRNA |
| 177250 | hu6-sgCebpd_v2 (opti) | Same as pLL3.3;U6(BstXI)-XhoI-chimeric RNA;PGK-Cre but XhoI stuffer removed, expresses Cebpd gRNA |
| 177251 | mU6-sgCebpa_v1-hu6-sgCebpb_v1 | Expresses Cebpa_v1 (mU6), Cebpb_v1 (hU6) gRNAs and Cre-recombinase |
| 177252 | mU6-sgCebpa_v2-hu6-sgCebpb_v2 | Expresses Cebpa_v2 (mU6), Cebpb_v2(hU6) gRNAs and Cre-recombinase |
| 177253 | mU6-sgCebpa_v1-hu6-sgCebpd_v1 | Expresses Cebpa_v1 (mU6), Cebpd_v1 (hU6) gRNAs and Cre-recombinase |
| 177254 | mU6-sgCebpa_v2-hu6-sgCebpd_v2 | Expresses Cebpa_v2 (mU6), Cebpd_v2(hU6) gRNAs and Cre-recombinase |
| 177255 | mU6-sgCebpb_v1-hu6-sgCebpd_v1 | Expresses Cebpb_v1 (mU6), Cebpd_v1 (hU6) gRNAs and Cre-recombinase |
| 177256 | mU6-sgCebpb_v2-hu6-sgCebpd_v2 | Expresses Cebpb_v2 (mU6), Cebpd_v2(hU6) gRNAs and Cre-recombinase |
| 177257 | bu6-sgCebpa_v1-mU6-sgCebpb_v1-hU6-sgCebpd_v1 | Expresses Cebpa_v1 (bU6), Cebpb_v1 (mU6), Cebpd_v1 (hU6) gRNAs and Cre-recombinase |
| 177258 | bu6-sgCebpa_v2-mU6-sgCebpb_v2-hU6-sgCebpd_v2 | Expresses Cebpa_v2 (bU6), Cebpb_v2 (mU6), Cebpd_v2 (hU6) gRNAs and Cre-recombinase |