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AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa.

Xue Y, Wang SK, Rana P, West ER, Hong CM, Feng H, Wu DM, Cepko CL
Elife. 2021 Apr 13;10. pii: 66240. doi: 10.7554/eLife.66240. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
206341AAV-RedO-Txnip(C247S)AAV plasmid expressing mutant TXNIP in photoreceptors
206343AAV-RO1.7-dnHIFAAV plasmid expressing dominant negative HIF1A in photoreceptors
206344AAV-Best1-Txnip(C247S_LL351-352AA)AAV plasmid expressing mutant TXNIP in retinal pigment epithelium

Antibodies from Article