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Engineering Extracellular Vesicles to Target Pancreatic Tissue In Vivo.

Komuro H, Kawai-Harada Y, Aminova S, Pascual N, Malik A, Contag CH, Harada M
Nanotheranostics. 2021 Apr 15;5(4):378-390. doi: 10.7150/ntno.54879. eCollection 2021. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
178424pcS-p88-C1C2p88 as a potential β-cell (pancreatic tissue) targeting peptide fused to EV membrane binding domain
178425pcS-mCherry-C1C2Fluorescence reporter fused to EV membrane binding domain for EV imaging and tracking
178426pcDNA-gLuc-C1C2Bioluminescence reporter fused to EV membrane binding domain for EV imaging and tracking
178427pcS-NP-C1C2Non peptide (NP) as negative control fused to EV membrane binging domain (C1C2)
178428pcS-pep1-C1C2pep1 as cell penetrating peptide fused to EV membrane binging domain (C1C2)

Antibodies from Article