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Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction.

Sharma S, Mukherjee AK, Roy SS, Bagri S, Lier S, Verma M, Sengupta A, Kumar M, Nesse G, Pandey DP, Chowdhury S
Cell Rep. 2021 May 18;35(7):109154. doi: 10.1016/j.celrep.2021.109154. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
192268CCR5_gRNA_pX459gRNA expression for CRISPR Genome Editing of CCR5
192269CCR5-donor-MCSDonor template for CRISPR Genome Editing
192270TERTpWT_Gluc_CCR5Donor template for insertion of hTERT promoter driven Gaussia luciferase reporter
192271TERTp124_Gluc_CCR5Donor template for insertion of hTERT promoter (-124 C to T) driven Gaussia luciferase reporter
192272TERTp146_Gluc_CCR5Donor template for insertion of hTERT promoter (-146 C to T) driven Gaussia luciferase reporter

Antibodies from Article