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PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.

Zhang Q, Agius SC, Flanigan SF, Uckelmann M, Levina V, Owen BM, Davidovich C
Nat Commun. 2021 Jul 28;12(1):4592. doi: 10.1038/s41467-021-24866-3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
191249PALI1_PIR_pFB1Expresses PALI1 from insect cells
191250ATOH1_pUC18Encodes the sequence for the ATOH1 gene (human)
191251LacZ_pHIVEGFPExpresses LacZ in mammalian cells (used as a control)
191252PALI1_pHIVEGFPExpresses PALI1 in mammalian cells

Antibodies from Article