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Spatial snapshots of amyloid precursor protein intramembrane processing via early endosome proteomics.

Park H, Hundley FV, Yu Q, Overmyer KA, Brademan DR, Serrano L, Paulo JA, Paoli JC, Swarup S, Coon JJ, Gygi SP, Wade Harper J
Nat Commun. 2022 Oct 16;13(1):6112. doi: 10.1038/s41467-022-33881-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
176487PX459-APP-KOTo knockout APP gene
176488pHAGE-3FLAG-RAB5AFor lentiviral transduction of 3FLAG-RAB5A
176489pHAGE-3FLAG-RAB11AFor lentiviral transduction of 3FLAG-RAB11A
176490pHAGE-3FLAG-TFR1For lentiviral transduction of 3FLAG-TFR1
176491pHAGE-3FLAG-EEA1For lentiviral transduction of 3FLAG-EEA1
177094pHAGE-APPSw;T719NFor lentiviral transduction of APPsw; T719N
193772pENTR221-APP751Entry vector for human APP isoform having 751 amino acid residues

Antibodies from Article