Tight nanoscale clustering of Fcgamma receptors using DNA origami promotes phagocytosis.
Kern N, Dong R, Douglas SM, Vale RD, Morrissey MA
eLife. 2021 Jun 3;10. pii: 68311. doi: 10.7554/eLife.68311.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
176606 | NK66 | To measure Syk intensity in response to ligand clustering using DNA origami |
176608 | NK72 | To test macrophage engulfment initiation. Lacks the FcyR chain. |
176609 | NK73 | To test bead engulfment of macrophages. |
176610 | NK83 | To measure Syk intensity in response to ligand clustering using DNA origami |
176611 | NK85 | To minimize dimerization between FcRg transmembrane domains, as this cysteine forms a disulfide bridge between y chains. To manipulate ligand spacing. |
176612 | NK88 | To manipulate ligand spacing. |