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Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.

Strong LM, Chang C, Riley JF, Boecker CA, Flower TG, Buffalo CZ, Ren X, Stavoe AK, Holzbaur EL, Hurley JH
Elife. 2021 Sep 10;10. pii: 70372. doi: 10.7554/eLife.70372. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
175026Halo-WIPI2B L69EExpresses WIPI2B (L69E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1
175027Halo-WIPI2B H85EExpresses WIPI2B (H85E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1
175028Halo-WIPI2B K88EExpresses WIPI2B (K88E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1
175029Halo-WIPI2B I92EExpresses WIPI2B (I92E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1
175030Halo-WIPI2B C93EExpresses WIPI2B (C93E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1
175031Halo-WIPI2B K128EExpresses WIPI2B (K128E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1
175032Halo-WIPI2B H85E K88EExpresses WIPI2B (H85E K88E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1
175033Halo-WIPI2B H85E K88E I92EExpresses WIPI2B (H85E K88E I92E) fused to Halo in mammalian cells to abrogate interaction with ATG16L1

Antibodies from Article