Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery.
Segel M, Lash B, Song J, Ladha A, Liu CC, Jin X, Mekhedov SL, Macrae RK, Koonin EV, Zhang F
Science. 2021 Aug 20;373(6557):882-889. doi: 10.1126/science.abg6155.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 174858 | pCMV-MmPeg10rc4 | Expresses recoded mouse Peg10 in mammalian cells |
| 174859 | pCMV-HsPeg10rc3 | Expresses recoded human Peg10 in mammalian cells |
| 174860 | pCMV-SynA | Expresses mouse syncytin A in mammalian cells |
| 174861 | pCMV-SynB | Expresses mouse syncytin B in mammalian cells |
| 174862 | pCMV-Mm.cargo(Cre) | Expresses mouse Peg10 cargoRNA encoding Cre recombinase |
| 174863 | pCMV-Hs.cargo(Cre) | Expresses human Peg10 cargoRNA encoding Cre recombinase |
| 174864 | pCMV-Hs.cargo(Cas9) | Expresses human Peg10 cargoRNA encoding SpCas9 |
| 174865 | pCMV-Mm.cargo(Cas9) | Expresses mouse Peg10 cargoRNA encoding SpCas9 |