The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.
Alejo-Valle O, Weigert K, Bhayadia R, Ng M, Issa H, Beyer C, Emmrich S, Schuschel K, Ihling C, Sinz A, Zimmermann M, Wickenhauser C, Flasinski M, Regenyi EM, Labuhn M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH
Blood. 2021 Sep 27. pii: S0006-4971(21)01649-9. doi: 10.1182/blood.2021012231.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 169296 | SIN40C.EFS.eGFP.ARID3A-3'UTR-Mut | Constitutive overexpression a mutated 3'UTR of the human ARID3A gene after a GFP, to evaluate miRNA binding. Regions not containing miR-125b or let-7c binding regions not included. |
| 169297 | SIN40C.EFS.eGFP.ARID3A-3'UTR-WT | Constitutive overexpression of the 3'UTR of the human ARID3A gene after a GFP, to evaluate miRNA binding. Regions not containing miR-125b or let-7c binding regions not included. |
| 169298 | SIN40C.EFS.eGFP.mArid3a-3'UTR-Mut | Constitutive overexpression a mutated 3'UTR of the murine Arid3a gene after a GFP, to evaluate miRNA binding. Regions not containing miR-125b or let-7c binding regions not included. |
| 169299 | SIN40C.EFS.eGFP.mArid3a-3'UTR-WT | Constitutive overexpression of the 3'UTR of the murine Arid3a gene after a GFP, to evaluate miRNA binding. Regions not containing miR-125b or let-7c binding regions not included. |
| 169300 | SIN40C.SFFV.ARID3a.IRES.GFP | Constitutive overexpression of human ARID3A cDNA with GFP as reporter fluorescent protein |
| 169301 | SIN40C.SFFV.dTomato.let-7c | Constitutive overexpression of let-7c with dTomato as a reporter fluorescent protein |
| 169302 | SIN40C.SFFV.dTomato.miR-125b-2 | Constitutive overexpression of miR-125b-2 with dTomato as a reporter fluorescent protein |
| 169303 | SIN40C.SFFV.dTomato.miR-ctrl | Constitutive overexpression of miR-ctrl with dTomato as a reporter fluorescent protein |
| 169304 | SIN40C.SFFV.GFP.miR-99a | Constitutive overexpression of miR-99a with GFP as a reporter fluorescent protein |
| 169305 | SIN40C.SFFV.GFP.miR-ctrl | Constitutive overexpression of miR-ctrl with GFP as a reporter fluorescent protein |
| 169306 | SIN40C.SFFV.KRAB-mArid3a.IRES.GFP | Constitutive overexpression of murine KRAB-Arid3a fusion protein with GFP as reporter fluorescent protein |
| 169307 | SIN40C.SFFV.Luciferase.IRES.dTomato | Constitutive overexpression of Luciferase cDNA with dTomato as a reporter fluorescent protein |
| 169308 | SIN40C.SFFV.Luciferase.IRES.GFP | Constitutive overexpression of Luciferase cDNA with GFP as a reporter fluorescent protein |
| 169309 | SIN40C.SFFV.mArid3a.IRES.GFP | Constitutive overexpression of murine Arid3a cDNA with GFP as reporter fluorescent protein |
| 169310 | SIN40C.SFFV.mTagBFP2.let-7c | Constitutive overexpression of let-7c with mTagBFP2 as a reporter fluorescent protein |
| 169311 | SIN40C.SFFV.mTagBFP2.miR-125b-2 | Constitutive overexpression of miR-125b-2 with mTagBFP2 as a reporter fluorescent protein |
| 169312 | SIN40C.SFFV.mTagBFP2.miR-ctrl | Constitutive overexpression of miR-ctrl with mTagBFP2 as a reporter fluorescent protein |
| 169313 | SIN40C.SFFV.VP64-mArid3a.IRES.GFP | Constitutive overexpression of murine VP64-Arid3a fusion protein with GFP as reporter fluorescent protein |
| 169314 | SIN40C.TRE.ARID3a.IRES.dTomato.PGK.sfGFP.P2A.Tet3G | Doxycycline-inducible expression of human ARID3A cDNA with dTomato as reporter fluorescent protein |
| 169315 | SIN40C.TRE.dTomato.miR-125b-2.PGK.sfGFP.P2A.Tet3G | Doxycycline-inducible expression of miR-125b-2 with dTomato as reporter fluorescent protein |
| 169316 | SIN40C.TRE.dTomato.miR-ctrl.PGK.sfGFP.P2A.Tet3G | Doxycycline-inducible expression of miR-ctrl with dTomato as reporter fluorescent protein |
| 169317 | SIN40C.TRE.Luciferase.IRES.dTomato.PGK.sfGFP.P2A.Tet3G | Doxycycline-inducible expression of Luciferase cDNA with dTomato as reporter fluorescent protein |
| 169318 | SIN40C.TRE.mArid3a.IRES.dTomato.PGK.sfGFP.P2A.Tet3G | Doxycycline-inducible expression of murine Arid3a cDNA with dTomato as reporter fluorescent protein |
| 174666 | SIN40C.TRE.mArid3a3xFLAG.IRES.dTomato.PGK.sfGFP.P2A.Tet3G | Doxycycline-inducible expression of murine Arid3a-3xFLAG cDNA with dTomato as reporter fluorescent protein |