Base editing screens map mutations affecting interferon-gamma signaling in cancer.
Coelho MA, Cooper S, Strauss ME, Karakoc E, Bhosle S, Goncalves E, Picco G, Burgold T, Cattaneo CM, Veninga V, Consonni S, Dincer C, Vieira SF, Gibson F, Barthorpe S, Hardy C, Rein J, Thomas M, Marioni J, Voest EE, Bassett A, Garnett MJ
Cancer Cell. 2023 Feb 13;41(2):288-303.e6. doi: 10.1016/j.ccell.2022.12.009. Epub 2023 Jan 19.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 174569 | iBE3 CLYBL | doxycycline inducible BE3 expression for human CLYBL locus knock-in |
| 174570 | iBE4max YE1 NG CLYBL | doxycycline inducible BE4max YE1 NG expression for human CLYBL locus knock-in |
| 174571 | HA-SOCS1 | Human HA-tagged SOCS1 expression (N-term. tag) (CMV prom.) |
| 174572 | FLAG-JAK1 | Human FLAG-tagged JAK1 expression (N-term. tag) (CMV prom.) |
| 174573 | FLAG-JAK1Gly590Arg | Human FLAG-tagged JAK1 Gly590Arg mutant expression (N-term. tag) (CMV prom.) |