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A rational blueprint for the design of chemically-controlled protein switches.

Shui S, Gainza P, Scheller L, Yang C, Kurumida Y, Rosset S, Georgeon S, Di Roberto RB, Castellanos-Rueda R, Reddy ST, Correia BE
Nat Commun. 2021 Oct 1;12(1):5754. doi: 10.1038/s41467-021-25735-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
174549S111Constitutive PhCMV-driven mammalian expression vector of CDH-1-TF cassette (PhCMV-Gal4-Bcl-XL-P2A-LD3-Rel65-pA)
174550S112Constitutive PhCMV-driven mammalian expression vector of CDH-2-TF cassette (PhCMV-Gal4-Bcl2-P2A-LD3-Rel65-pA)
174551S113Constitutive PhCMV-driven mammalian expression vector of CDH-3-TF cassette (PhCMV-Gal4-mdm2-P2A-LD6-Rel65-pA)
174552S019pET-iBclxL-v3, His tag for affinity purification
174553S330pET-iBcl2-v4, His tag for affinity purification

Antibodies from Article