Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase.
Dietz JV, Willoughby MM, Piel RB 3rd, Ross TA, Bohovych I, Addis HG, Fox JL, Lanzilotta WN, Dailey HA, Wohlschlegel JA, Reddi AR, Medlock AE, Khalimonchuk O
Redox Biol. 2021 Oct;46:102125. doi: 10.1016/j.redox.2021.102125. Epub 2021 Sep 10.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 174524 | pRS426-HsFECH | Expresses human ferrochelatase (FECH) in yeast |
| 174525 | pRS423-mitoT | Expresses yeast variant of mitoT synthetic intermembrane tether bridging the inner and outer mitochondrial membranes |