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CSF-1/CSF-1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-Cell Infiltration in the Sarcoma Microenvironment.

Fujiwara T, Yakoub MA, Chandler A, Christ AB, Yang G, Ouerfelli O, Rajasekhar VK, Yoshida A, Kondo H, Hata T, Tazawa H, Dogan Y, Moore MAS, Fujiwara T, Ozaki T, Purdue E, Healey JH
Mol Cancer Ther. 2021 Jun 4. pii: 1535-7163.MCT-20-0591. doi: 10.1158/1535-7163.MCT-20-0591. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
48688pUltra-Chili-Luc3rd generation Lentiviral vector with bi-cistronic expression of dtomato and luciferase

Antibodies from Article