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Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.

Xia Z, Tang M, Ma J, Zhang H, Gimple RC, Prager BC, Tang H, Sun C, Liu F, Lin P, Mei Y, Du R, Rich JN, Xie Q
Nucleic Acids Res. 2021 Jul 21;49(13):7361-7374. doi: 10.1093/nar/gkab517. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
174218pMSCV-dCasRx-METTL3-PUROExpresses dCasRx-METTL3 in mammalian cell
175582pMSCV-dCasRx-ALKBH5-PUROExpresses dCasRx-ALKBH5 in mammalian cell
175583lenti-sgRNA-BSDExpresses sgRNA for CasRx in mammalian cell

Antibodies from Article