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Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.

Zimmet A, Van Eeuwen T, Boczkowska M, Rebowski G, Murakami K, Dominguez R
Sci Adv. 2020 Jun 5;6(23). pii: 6/23/eaaz7651. doi: 10.1126/sciadv.aaz7651. Print 2020 Jun. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
173676Arp2_pLibArp2 subunit of the Human Arp2/3 complex in a library vector for the biGBac system of insect expression
173677Arp3_pLibArp3 subunit of the Human Arp2/3 complex in a library vector for the biGBac system of insect expression
173678ArpC1_pLibArpC1 subunit of the Human Arp2/3 complex in a library vector for the biGBac system of insect expression
173679ArpC2_pLibArpC2 subunit of the Human Arp2/3 complex in a library vector for the biGBac system of insect expression
173680ArpC3-FLAG_pLibArpC3 subunit of the Human Arp2/3 complex in a library vector for the biGBac system of insect expression
173681ArpC4_pLibArpC4 subunit of the Human Arp2/3 complex in a library vector for the biGBac system of insect expression
173682ArpC5_pLibArpC5 subunit of the Human Arp2/3 complex in a library vector for the biGBac system of insect expression
173683Arp2/3_pBIG2abcdInsect expression of the 7-subunit Human Arp2/3 complex

Antibodies from Article