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A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance.

Reinhart EF, Litt NA, Katzenell S, Pellegrini M, Yamamoto A, Ragusa MJ
Traffic. 2021 Jan;22(1-2):23-37. doi: 10.1111/tra.12771. Epub 2020 Dec 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
197045ALFY-FYVE 1GExpression plasmid for the FYVE domain from ALFY for recombinant expression in E. coli.

Antibodies from Article