Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates.
Marchak A, Grant PA, Neilson KM, Datta Majumdar H, Yaklichkin S, Johnson D, Moody SA
Dev Biol. 2017 Sep 1;429(1):213-224. doi: 10.1016/j.ydbio.2017.06.025. Epub 2017 Jun 27.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 172463 | pCS2+-wbp2nl | expresses wild-type protein when injected into embryos |
| 172464 | pCS2+-wbp2nlT45A | expresses protein with one aa substitution to affect potential phosphorylation |
| 172466 | pCS2+-wbp2nlY55F | expresses protein with one aa substitution to affect potential phosphorylation in ITSM domain |
| 172467 | pCS2+5'MT-wbp2nl | expresses myc-tagged version of wild-type protein |
| 172468 | pCS2+-wbp2nlY282F | expresses protein with one aa substitution to affect potential phosphorylation in WW-interaction domain |
| 174507 | pCS2+-wbp2nlF127P | expresses protein with one aa substitution to disrupt the alpha-helix near the PH-G domain |
| 174791 | pCS2+WBP2NL-HA | Xenopus laevis WBP2NL with 3'HA tag |